To explore the intervention mechanism of acupuncture in treating obesity with dampness syndrome combined with abnormal glucose metabolism based on intestinal microbiota and neural regulatory network

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300074350

Enrollment

Unknown

Registered

2023-08-04

Start date

2023-08-07

Completion date

Unknown

Last updated

2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity combined with abnormal glucose metabolism

Interventions

Acupuncture group:The patient was positioned supine, and after routine sterilization of the acupuncture points, disposable sterile needles were used to acupuncture Zhongwan, Tianshu (double), Shui Dao

Pseudo-needling group:The patient was positioned supine, and the acupuncture points were routinely sterilized, and the sham acupuncture needles were used to contact but not penetrate the skin, and to

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ? Age 18-65 years old, male and female; ?It meets the criteria for diagnosis of obesity, abnormal glucose metabolism and differentiation of dampness syndrome; ?Relatively stable eating habits, no special diet preference, no serious bad habits such as long-term heavy smoking, alcoholism, drug addiction in the past 5 years; ? have not received acupuncture weight loss treatment in the past three months; ? Voluntarily join and sign the informed consent.

Exclusion criteria

Exclusion criteria: ? combined with acute infectious diseases; ? Patients with severe hepatic and renal insufficiency, heart disease, respiratory disease and malignant tumor; ?Previous blood system diseases such as chronic liver disease, coagulopathy, acute and chronic gastrointestinal diseases such as chronic inflammation of the gastrointestinal tract, Crohn's disease, gastrointestinal tumors, and gastrointestinal surgery history may lead to intestinal flora disorders; ? Antibiotics, laxatives, probiotics or prebiotics have been used within 1 month before or before enrollment; ? Patients with metabolic diseases such as severe hyperuricemia and hyperlipidemia and poor drug control; ? Patients with mental and emotional diseases, unable to cooperate with researchers; ? Pregnant women, pregnancy, perinatal, lactating women, perioperative patients; ? Normal for allergic constitution, allergic to needles; ? Patients with skin diseases or skin damage at the needling site.

Design outcomes

Primary

Measure	Time frame
Body Mass Index;	—

Secondary

Measure	Time frame
waist;hipline;waist hip rate;weight;body fat rate;Fecal metabolomics;fasting blood-glucose;glycosylated hemoglobin;fasting insulin;	—

Countries

China

Contacts

Public ContactZeng Huiyan

Guangdong Provincial Hospital of Chinese Medicine

13924011881@126.com+86 139 2401 1881

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026