Skip to content

Effect of oral dclonine mucilage on laryngopharyngeal pain after general anesthesia

Effect of oral dclonine mucilage on laryngopharyngeal pain after general anesthesia

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074345
Enrollment
Unknown
Registered
2023-08-04
Start date
2023-08-06
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat

Interventions

Con Group (TI):Patients with tracheal intubation and general anesthesia should take normal saline before anesthesia induction
Dyc Group (TI):In patients with tracheal intubation and general anesthesia, dclonine was administered before induction of anesthesia
Con Group (LM):For patients with laryngeal mask anesthesia, normal saline should be administered before anesthesia induction
Dyc Group (LM):In patients with laryngeal mask anesthesia, dclonine paste was administered before anesthesia induction

Sponsors

The First Affiliated Hospital of University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients under general anesthesia with tracheal intubation or laryngeal mask; ASA Level I-III; Age 18-70 years old; The expected mechanical ventilation time is less than or equal to 4h.

Exclusion criteria

Exclusion criteria: People with a history of mental illness or long-term use of psychotropic drugs; Allergic to local anesthetics; Patients with decompensated heart (NYHA heart function grade III and above), liver (Child grade C), kidney (maintenance dialysis) and other vital system organ diseases; Patients with chronic respiratory disease, asthma history, chronic pharyngitis history, sore throat or hoarseness; Patients undergoing head and neck surgery, oropharyngeal surgery and heart surgery; Patients with airway injury or compression, assessed as having a difficult airway; Patients who have previously undergone radical surgery for esophageal or gastric cancer; Have a history of structural lesions or surgery in the throat; Declined to participate in the study or is participating in other researchers.

Design outcomes

Primary

MeasureTime frame
VAS score of postoperative sore throat;Pharyngeal pain was graded by Prince-Henry score;

Secondary

MeasureTime frame
The occurrence of hoarseness;HR,BP,SPO2;

Countries

China

Contacts

Public ContactXie Yanhu

The First Affiliated Hospital of University of Science and Technology of China

xyh200701@sina.cn+86 139 5601 3081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026