Postoperative cognitive dysfunction
Conditions
Interventions
TWO group:In the experimental group, the tidal volume was adjusted by 6-8ml/kg, the respiratory rate was 10-16 times/min, I:E=1:2, and the PaCO2 range was maintained at 55-65mmHg, and the blood gas an
Sponsors
The First Affiliated Hospital of the University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Patients undergoing laparoscopic surgery with head-low foot high or head-high-foot position; (2) Between the ages of 65 and 85; (3)18.5=BMI=23.9 (4)ASA I, II, III; NYHAI, II;
Exclusion criteria
Exclusion criteria: 1. Preoperative mini mental state scale, score less than or equal to 23 points. 2. Have a serious history of mental or nervous system; Have a history of drug or psychotropic substance abuse; Severe visual or hearing impairment 3. The patient had Alzheimer's disease before operation. 4. The patient suffered from severe lung disease before operation, which affected the normal ventilation function. 5. There are other serious systemic diseases or the study doctor thinks that the patient can't enter the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| regional cerebral oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative cognitive dysfunction; | — |
Countries
China
Contacts
Public ContactWei Xin
The First Affiliated Hospital of the University of Science and Technology of China
Outcome results
None listed