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Retrospective and prospective cohort study of tuberculosis risk with biologic therapy for psoriasis

Retrospective and prospective cohort study of tuberculosis risk with biologic therapy for psoriasis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074332
Enrollment
Unknown
Registered
2023-08-03
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psoriasis

Interventions

Application of IL-17A in the treatment of LTBI patients with psoriasis and anti-tuberculosis therapy:NA
Treatment of LTBI patients with psoriasis using IL-17A without anti-tuberculosis therapy:NA
Apply TNF a LTBI patients treating psoriasis:NA

Sponsors

Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. From August 3rd, 2020 to August 3rd, 2023, all patients who were clinically diagnosed with psoriasis in 5-6 sub-centers of the National Psoriasis Diagnosis and Treatment Center Database and received biologic therapy were included. 2. Those who agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Active tuberculosis: The patient's medical history, clinical symptoms and examination results before biologics treatment suggest that the patient has active tuberculosis; 2. Pregnant women, lactating women and other patients who are not suitable for treatment; 3. Patients who cannot cooperate with the completion of tuberculosis-related laboratory tests; 4. Patients who cannot cooperate with follow-up.

Design outcomes

Primary

MeasureTime frame
Active tuberculosis incidence;Active tuberculosis incidence density;

Countries

china

Contacts

Public ContactYi Zhao

Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University

zhaoyi@btch.edu.cn+86 137 1864 6181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026