Knee Osteoarthritis
Conditions
Interventions
Case series (Retrospective part):None
Sponsors
West China Hosipital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with knee osteoarthritis according to the 'Chinese guideline for diagnosis and treatment of osteoarthritis(2021 edition)' published in the Chinese Journal of Orthopaedics: Individual meet criteria of 1) + ( any two of 2), 3), 4), 5)) can be diagnosed: 1) Repeated knee pain in the past 1 month; 2) X-ray film (standing position or weight-bearing position) showed narrowed joint space, subchondral bone sclerosis and/or cystic degeneration, osteophyte formation at joint edge; 3) Age >= 50 years old; 4) Stiffness at morning = 40; 3. Receive PRP treatment at least one time; 4. Under 80 years old; 5. Willing to comply with the treatment plan and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Combine one or more non-knee problems in lower limb that affect daily activities; 2. Intra-articular injection of steroids or PRP and other biological agents within 8 weeks; 3. Multiple body parts injection conducted at the same time ; 4. Recieved other treatments that may have an impact on the observation indicators of PRP treatment in the past year, such as biological therapy including stem cells, and systemic immunosuppressive drugs; 5. Pregnant and lactating women; 6. With infectious diseases; 7. Fever > 38.0 centigrade of unknown origin within three days; 8. History of alcohol and drug abuse; 9. Moderate to severe anxiety, depression and other mental illness; 10. Do not understand Mandarin, do not understand Chinese characters.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;WOMAC; | — |
Countries
China
Contacts
Public ContactHongchen He
West China Hospital of Sichuan University
Outcome results
None listed