Acute Respiratory Distress Syndrome
Conditions
Interventions
A group:Perform the first stage operation first, and then the second stage operation. Each phase lasted 2 hours, followed by the detection of the lung shunt and dead space and oxygenation-related para
group B:Perform the second stage operation first, and then the first stage operation. Each phase lasted 2 hours, followed by the detection of the lung shunt and dead space and oxygenation-related para
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Meets the ARDS Berlin definition; Expected mechanical ventilation duration of more than 24 hours; Deep vein indwelling
Exclusion criteria
Exclusion criteria: • Age < 18 years old • Pregnancy • Chest malformations • SpO2 < 88% when oxygen concentration is above 70% • Contraindications in EIT use (e.g., automatic implantable cardioverter defibrillators and implantable heart pumps) • Extremely unstable hemodynamics (norepinephrine application above 0.5ug/kg/min can maintain a systolic blood pressure of 90mmHg or mean arterial pressure of 65mmHg) • Blood sodium over 150mmol/L • Undrained pneumothorax • Patients with chronic renal failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| dead space;shunt;PaCO2;lung compliance; | — |
Countries
China
Contacts
Public ContactLiu JIalin
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed