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Effects of perinatal and extraneonatal environment on oxidative stress status, maternal and infant outcomes, and interventional studies

Effects of perinatal and extraneonatal environment on oxidative stress status, maternal and infant outcomes, and interventional studies

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074300
Enrollment
Unknown
Registered
2023-08-03
Start date
2023-08-14
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension during pregnancy

Interventions

Intervention Group 1:On the basis of the control group, the Dash diet model + exercise intervention was implemented using the mobile platform guided by the theory of planned behavior
Intervention Group 2:On the basis of the control group, the theory of planned behavior (TPB) was used as the guidance to implement the Mediterranean diet model + exercise using a mobile platform
Intervention Group 3:On the basis of the control group, the theory of planned behavior(TPB) was used as the guidance, and the mobile platform was used to implement a balanced diet pattern + exercise
Control group:Routine antenatal care, outpatient antenatal care and health education

Sponsors

Dongguan Maternal and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for the previous investigational studies in this study: (1) According to the diagnostic criteria of the 2020 version of the guidelines for the diagnosis and treatment of hypertension diseases in pregnancy, hypertension appeared for the first time after 20 weeks' gestation, with systolic blood pressure = 140 mm Hg and/or diastolic blood pressure = 90 mm Hg; (2) Have complete cognitive and behavioral ability, good communication and expression skills; (3) Informed consent and voluntary participation in this research and research Inclusion criteria for interventional studies: (1) hypertension for the first time after 20 weeks' gestation, systolic blood pressure = 140 mm Hg and/or diastolic blood pressure = 90 mm Hg according to the 2020 version of the guidelines for the diagnosis and treatment of hypertension disorders in pregnancy; (2) singletons; gestational weeks 20-37 weeks; 18 years of age or older (3) Have complete cognitive and behavioral ability, good communication and expression skills; (4) Informed consent and voluntary participation in this research and research (5) Proficient in the use of smartphones

Exclusion criteria

Exclusion criteria: Exclusion Criteria for Investigative Studies: (1) Severe heart, liver, lung, kidney damage, chronic hypertension combined with pregnancy (2) Age< 18 years old; (3) pregnant women with acute pregnancy complications; (4) suffering from mental, cognitive or mental illness; Exclusion criteria for interventional studies: (1) Severe heart, liver, lung and kidney damage; Chronic hypertension with pregnancy; (2) severe preeclampsia; (3) presence of movement disorders; (4) has been treated with oral antihypertensive drugs; (5) suffering from mental, cognitive or mental illness; (6) pregnant women with acute pregnancy complications; (7) Gestational diabetes, diabetes mellitus combined with pregnancy, placenta previa after 26 weeks of pregnancy, cervical insufficiency, (8) Vaginal bleeding in the second and third trimesters of ongoing pregnancy, multiple pregnancy

Design outcomes

Primary

MeasureTime frame
Blood pressure;

Secondary

MeasureTime frame
Hypertension self-management behavior scale;Hypertensive disorders in Pregnancy Knowledge questionnaire;Pittsburgh sleep quality fares;Theory of planned Behavior questionnaire for hypertension in pregnancy;AOPPs;sFLT-1/PLGF;ACR;The incidence of adverse pregnancy outcomes;Blood lipids;The DASH dietary adherence score;The Alternative Mediterranean Diet Adherence Score;Dietary balance index during pregnancy;Food frequency;

Countries

China

Contacts

Public ContactJianying Zhu

Dongguan Maternal and Child Health Care Hospital

zhujianying9@163.com+86 137 1330 1332

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026