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A multicenter clinical study on the inhibitory effect of single and repeated administration of muscle relaxants on obturator nerve reflex during TURBT

A multicenter clinical study on the inhibitory effect of single and repeated administration of muscle relaxants on obturator nerve reflex during TURBT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074294
Enrollment
Unknown
Registered
2023-08-03
Start date
2023-08-11
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer

Interventions

experimental group:Repeated doses of muscle relaxants were given
control group:Single dose of muscle relaxant rocuronium bromide

Sponsors

The Second Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Superficial tumors of the lateral wall and triangle of the bladder 2.Single or multiple superficial tumors = 1cm in diameter. 3.Muscular invasive bladder tumor that cannot tolerate radical cystectomy 4.The patient was a muscle-invasive bladder tumor with bladder preservation undergoing TURBT.

Exclusion criteria

Exclusion criteria: 1.Single superficial tumor < 1cm in diameter. 2.Patients who could not tolerate general anesthesia intubation due to general condition 3.Allergic patients to anesthetics used in the study 4.Patients with urinary tract infections that have not been effectively controlled 5.Patients with urethral stricture who cannot be implanted with resectoscope 6.Patients during pregnancy 7.Patients with incomplete clinical data collection

Design outcomes

Primary

MeasureTime frame
Classification of obturator nerve reflex in TURBT;Tumor resection time;

Secondary

MeasureTime frame
Preoperative hemoglobin;operation time;Intraoperative and postoperative blood transfusion;Bladder perforation;Hemoglobin on the first day after operation;

Countries

China

Contacts

Public ContactLi Jiongming

The Second Affiliated Hospital of Kunming Medical University

jiongmingli@aliyun.com+86 137 0841 6552

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026