carotid atherosclerosis with hyperlipidemia
Conditions
Interventions
Sponsors
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) 3 0 years old< age < 75 years old; (2) Meet the diagnostic criteria for primary hyperlipidemia and meet any of the following: TC=5.2mmol/L; LDL-C=3.4mmol/L; TG:1.7-5.2mmol/L; (3) Vascular ultrasound confirmed that it met the diagnostic criteria for carotid atherosclerosis, carotid intimal thickness (IMT) and carotid artery stenosis < 50%; (4) TCM differentiation is a mutual certificate of stasis; (5) Although taking lipid-lowering drugs, they have been discontinued for 2 weeks or more. (6) Voluntarily participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Previously diagnosed coronary heart disease, or uncontrolled hypertension (sitting diastolic blood pressure = 100 mmHg or systolic blood pressure =160 mmHg), or diabetes mellitus (glycosylated hemoglobin (HbA1c) =8.5%), or uncontrolled heart failure (NYHA grade = grade III) and arrhythmias with clinical symptoms or hemodynamic disorders; (2) Hyperlipidemia caused by drugs (phenothiazines, ß-blockers, adrenal corticosteroids and certain contraceptives, etc.), or patients who are using hormones, thyroxine therapy drugs and other drugs that affect blood lipid metabolism; (3) Combined with major diseases of liver, kidney and blood system, major infectious diseases, active rheumatic immune diseases, malignant tumors and psychosis; (4) Those who have had severe trauma or major surgery in the past six months, or have bleeding tendency; (5) Women who are currently or planning to be pregnant or lactating, or who are allergic to the test drug or the ingredients contained therein; (6) Those who participate in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LDL-C;Carotid Intima-Media Thickness ; | — |
Secondary
| Measure | Time frame |
|---|---|
| TC;TG;HDL-C;plaque area;Integral of TCM Syndrome; | — |
Countries
China
Contacts
Public ContactMei Xue/Lizhi LI
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Outcome results
None listed