dilated cardiomyopathy
Conditions
Interventions
Gold Standard:Cardiac ultrasound: (1) left ventricular end-diastolic diameter (LVEDd) greater than 5.0 cm in women or 5.5 cm in men
and (2) left ventricular ejection fraction (LVEF) less than 45% according to the Teichholtz method.
Coronary angiography: All participants underwent percutaneous coronary angiography to assess coronar
Index test:Non targeted metabolomics analysis data
Sponsors
The First Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria were as follows: The selection was based on the recommendations for the diagnosis and treatment of cardiomyopathy issued by China in 2007 and foreign guidelines (AHA 2006 and ESC 2008): 1) left ventricular end-diastolic diameter (LVEDD) >5.5 cm, and left ventricular ejection fraction (LVEF) <45%. LVEDD and ejection fraction were measured by echocardiography; 2) meet the recommendations for the diagnosis and treatment of cardiomyopathy issued by China in 2007, and the criteria of AHA 2006 and ESC 2008 guidelines; 3) intention to undergo coronary angiography during hospitalisation.
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: 1) other cardiomyopathies, including hypertrophic cardiomyopathy, restrictive cardiomyopathy, perinatal cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, etc.; 2) long-standing uncontrolled hypertension (160/100 mmHg), history of excessive alcohol intake (>2 taels/day for men, >1 taels/day for women), hyperthyroidism, anaemia, etc.; 3) combination of other diseases that can cause myocardial damage, such as valvular disease, congenital heart disease, pulmonary heart disease, etc.; 4) myocarditis and acute dilated cardiomyopathy caused by it; 4) myocarditis and its causes. heart disease, pulmonary heart disease, etc.; 4) myocarditis and acute dilated cardiomyopathy caused by other diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exploring the feasibility of faecal and urinary untargeted metabolomic profiles for the non-invasive diagnosis of cardiomyopathy subtypes, that is its concordance with ultrasound and coronary angiography results;Area under the receiver operating characteristic curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specifity; | — |
Countries
China
Contacts
Public ContactYandan Xie
The First Affiliated Hospital of Shantou University Medical College
Outcome results
None listed