Renal transplantation immunosuppression
Conditions
Interventions
experimental group:Mizoribine
Contrast group:Mycophenolate Mofetil
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) After donor kidney transplantation; 2) Adult recipients aged 18-75 years, regardless of gender; 3) First-time kidney transplant recipients; 4) Voluntarily sign written informed consent.
Exclusion criteria
Exclusion criteria: 1) Multiple organ transplantation; 2) DSA positive patients had ABO incompatibility and PRA>30%; 3) Recipients with active signs of infection; 4) Recipients with leukocyte counts below 3,000/mm3; 5) Pregnant women, breastfeeding women or women who do not wish to use appropriate contraceptive methods during the study period; 6) Patients with severe gastrointestinal diseases and active peptic ulcer disease; 7) suffering from any mental illness; 8) Patients with severe heart disease and abnormal heart function; 9) Subjects who are known to be allergic to the test drug; 10) Recipients judged unsuitable for inclusion by other competent physicians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of acute rejection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recipient survival rate;Survival rate of transplanted kidney; | — |
Countries
China
Contacts
Public ContactTAO LIN
West China Hospital, Sichuan University
Outcome results
None listed