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Changes of ocular surface and corneal biological characteristics and clinical analysis in diabetes patients

Changes of ocular surface and corneal biological characteristics and clinical analysis in diabetes patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074259
Enrollment
Unknown
Registered
2023-08-02
Start date
2023-08-10
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, dry eye, keratopathy

Interventions

Case series:Case series

Sponsors

Shandong Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age range: 50-80 Diagnosis: Previous and current diagnosis of diabetes, i.e. fasting blood glucose (FPG)>7.0mmol/L, or blood glucose associated with diabetes symptoms>11.1mmol/L, or blood glucose 2 hours after glucose load (OGTT2h)>7.8mmol/L

Exclusion criteria

Exclusion criteria: Previous eye surgery history, previous eye trauma history, use of eye surface drugs in the past three months, except for artificial tears, wearing contact lenses in the past three months, confirmed Sjogren's syndrome, rheumatoid arthritis, confirmed other peripheral neuropathy, and severe systemic diseases

Design outcomes

Primary

MeasureTime frame
Confocal microscopy corneal nerve related parameters;Tear film rupture time;Schirmer I test;Corneal perception test;Sodium fluorescein staining of cornea;OSDI score;Height of lacrimal river;Morphology of Meibomian gland;

Countries

China

Contacts

Public ContactTing Wang

Shandong Eye Hospital

wt-ting@163.com+86 138 6918 2795

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026