Effect of loxoprofen sodium patch on patients after unicompartmental arthroplasty: a prospective clinical study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300074245

Enrollment

Unknown

Registered

2023-08-02

Start date

2023-08-08

Completion date

Unknown

Last updated

2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Study group:Topical nonsteroidal antiinflam-matory drug (NASID)

Control group:Topical placebo

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Simple unilateral interventricular osteoarthritis of knee joint; 2. Internal and external inversion deformity less than 20°, flexion contracture less than 30°; 3. The function of anterior and posterior cruciate ligaments and collateral ligaments is intact.

Exclusion criteria

Exclusion criteria: 1. Rheumatoid and other inflammatory arthritis 2. Neuromuscular disorders affecting joint functio 3. Had a hip replacement

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale (VAS) of knee joint;The consumption of opioids;	—

Secondary

Measure	Time frame
The time of first analgesic demand of patient-controlled analgesia (PCA);Operation time;Side effects of opioids;Postoperative hospital stay;American Knee Society Score;Surgery-related complication;Wound healing grade postoperatively;	—

Countries

China

Contacts

Public ContactPeilai Liu

Qilu Hospital of Shandong University

gklpl@163.com+86 185 6008 2583

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026