preterm labor
Conditions
Interventions
Emergency Cervical Cerclage:emergency cervical cerclage
Control:bed rest
Sponsors
Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital Of Nanjing University Medical School
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: alive twin pregnancies between 24 weeks 0/7 days of gestation and 27 weeks 6/7 days of gestation, cervical dilation of 1 to 5 cm by speculum examination, intact membranes, understanding and signing informed consent
Exclusion criteria
Exclusion criteria: ? preterm labor ? clinical envidences of chorioamnionitis,severe abdominal pain or envidences of infection ? continuous vaginal bleeding ? premature rupture of membranes ? cervical dilation > 5 cm ?special complications of monochorionic diamniotic twins or monoamniotic twins ? Fetal distress, severe birth defects or single intrauterine fetal death ? Other pregnancy contraindications such as severe preeclampsia, severe internal and surgical diseases ?refusal of randomization, inability to sign consent, cognitive or intellectual disability, inability to read or write Chinese language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| preterm births at <32 weeks of gestation; | — |
Secondary
| Measure | Time frame |
|---|---|
| preterm births at <28 weeks of gestation;preterm births at <34 weeks of gestation;preterm births at <37 weeks of gestation;perinatal mortality;interval from surgery to delivery;live birth rate;adverse neonatal outcome;Incidence of chorioamnionitis; | — |
Countries
China
Contacts
Public ContactYimin Dai
Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital Of Nanjing University Medical School
Outcome results
None listed