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Genetic Association Study on Individual Differences in the Control Effect of Corneal Shapers on Myopia in Children

Genetic Association Study on Individual Differences in the Control Effect of Corneal Shapers on Myopia in Children

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074228
Enrollment
Unknown
Registered
2023-08-01
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

Good control effect group (100 cases, wearing corneal reshaping lenses with an annual increase of eye axis less than 0.1mm):NA
Poor control effect group (100 cases, wearing corneal reshaping lenses with an annual increase of eye axis greater than 0.4mm):NA

Sponsors

Affiliated Eye Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 12 Years

Inclusion criteria

Inclusion criteria: The age at which one begins to wear corneal shapescopes is 8-12 years old, and one has been or can wear corneal shapescopes regularly for one year; Baseline non Ciliary muscle paralysis subjective refraction: -6.00 D = binocular equivalent spherical lens degree = -1.00D, astigmatism = 1.50D, anisometropia = 1.50D.

Exclusion criteria

Exclusion criteria: Suffering from cardiovascular dysfunction, liver and kidney dysfunction, and immune system related diseases; Or suffer from eye diseases that affect vision or Refractive error, such as cataract and other lens damage diseases, glaucoma, fundus myopia damage, hereditary macular disease, keratopathy, Uveitis, Retinal detachment, severe vitreous opacity, etc; Amblyopia, intermittent strabismus, and dominant strabismus; During the first year of wearing corneal shaping glasses, I used Atropine, gualencic and other myopia control drugs; Or have used Atropine, multifocal soft glasses, functional frame glasses, or had adjustment training or Chinese medicine ear point pressing therapy within 3 months before wearing corneal shaping glasses.

Design outcomes

Primary

MeasureTime frame
Elongation of axial length;High throughput sequencing Genetic testing;

Countries

China

Contacts

Public ContactWu Hao

Affiliated Eye Hospital of Wenzhou Medical University

wuhao@eye.ac.cn+86 159 5871 0273

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026