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Chest Compression for Treatment of Respiratory Depression in elderly Patients Under Deep Sedation During Upper Gastrointestinal Endoscopy: A single-center prospective randomized controlled study

Chest Compression for Treatment of Respiratory Depression in elderly Patients Under Deep Sedation During Upper Gastrointestinal Endoscopy: A single-center prospective randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074221
Enrollment
Unknown
Registered
2023-08-01
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory depression

Interventions

Experimental group:Modified Manual Chest Compression + Conventional measures such as opening the airway to increase oxygen flow
control group:Conventional measures such as opening the airway to increase oxygen flow

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: ?Patients participate voluntarily and sign informed consent; ? Plan to perform painless gastroscopy in outpatient department; ?Age = 65 years; ?ASA ?-? grade

Exclusion criteria

Exclusion criteria: (1) The patient refuses to participate in this study or is participating in other clinical trials; (2) Serious dysfunction of important organs, including severe heart, lung, liver, and kidney dysfunction; (3) Combined with severe coagulation dysfunction; (4) History of thoracic deformity and rib fracture, thoracic and abdominal trauma, and surgery; (5) The basal blood oxygen saturation caused by various reasons is less than 95%; (6) Those who cannot cooperate with follow-up due to a history of neurological or psychiatric diseases or other reasons; (7) Serious complications during the examination, such as heavy bleeding, organ damage, etc.; (8) Those who are lost to follow-up or fail to follow up as required.

Design outcomes

Primary

MeasureTime frame
Whether SpO2 is back up to 95%;the time of SpO2 recovers to 95% ;

Secondary

MeasureTime frame
Incidence of subclinical respiratory depression;Incidence of hypoxemia;Incidence of severe hypoxemia;The lowest value of SpO2;Whether there is a pause in breathing;Whether a discontinued examination is required for mask-assisted breathing;Whether endotracheal intubation is required;SpO2;Noninvasive systolic blood pressure;Noninvasive diastolic blood pressure;Noninvasive mean arterial pressure;heart rate;Diaphragmatic range of motion;respiratory rate;Tidal volume;end-tidal CO2;bispectral index;Propofol dosage;Total inspection time;Wake up time;Adverse reactions within 24 hours after operation;Gastroscopist satisfaction score;Patient satisfaction scores;

Countries

China

Contacts

Public ContactLi Xiaoyun

The Third Affiliated Hospital of Sun Yat-sen University

13113361686@126.com+86 131 1336 1686

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026