Respiratory depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ?Patients participate voluntarily and sign informed consent; ? Plan to perform painless gastroscopy in outpatient department; ?Age = 65 years; ?ASA ?-? grade
Exclusion criteria
Exclusion criteria: (1) The patient refuses to participate in this study or is participating in other clinical trials; (2) Serious dysfunction of important organs, including severe heart, lung, liver, and kidney dysfunction; (3) Combined with severe coagulation dysfunction; (4) History of thoracic deformity and rib fracture, thoracic and abdominal trauma, and surgery; (5) The basal blood oxygen saturation caused by various reasons is less than 95%; (6) Those who cannot cooperate with follow-up due to a history of neurological or psychiatric diseases or other reasons; (7) Serious complications during the examination, such as heavy bleeding, organ damage, etc.; (8) Those who are lost to follow-up or fail to follow up as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether SpO2 is back up to 95%;the time of SpO2 recovers to 95% ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of subclinical respiratory depression;Incidence of hypoxemia;Incidence of severe hypoxemia;The lowest value of SpO2;Whether there is a pause in breathing;Whether a discontinued examination is required for mask-assisted breathing;Whether endotracheal intubation is required;SpO2;Noninvasive systolic blood pressure;Noninvasive diastolic blood pressure;Noninvasive mean arterial pressure;heart rate;Diaphragmatic range of motion;respiratory rate;Tidal volume;end-tidal CO2;bispectral index;Propofol dosage;Total inspection time;Wake up time;Adverse reactions within 24 hours after operation;Gastroscopist satisfaction score;Patient satisfaction scores; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Sun Yat-sen University