Study on the sedative effect of painless gastroscopy in obese patients
Conditions
Interventions
Cyclopofol Group:Cyclopofol + sufentanil
Propofol group:Propofol + sufentanil
Sponsors
Hangzhou Red Cross Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients intending to undergo painless gastroscopy;(2) AmericanSociety of Anesthesiologists (ASA) grade II;(3) Age 18-65 years old;(4) BMI=28kg/m
Exclusion criteria
Exclusion criteria: (1) Have a history of allergy to the drugs involved in the study;(2) A history of upper respiratory tract infection within two weeks;(3) Asthma attacks, uncontrolled hypertension, diabetes, hyperthyroidism or hypothyroidism;(4) mental system diseases (such as schizophrenia, depression, etc.), epilepsy history and cognitive dysfunction;(5) Have a history of psychotropic drug and narcotic drug abuse;(6) Abnormal liver function, renal function and coagulation function;(7) Pregnant or lactating women;(8) RR 24 times/min in screening period or baseline period, SpO2 < 95% when breathing air.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypoxia (SPO2<90%); | — |
Secondary
| Measure | Time frame |
|---|---|
| The patient needed airway operations during surgery;endoscope extractions due to hypoxia;Time for painless gastroscopy;Total dosage of cyclopofol & Propofol;MAP HR SPO2 MOAA/S values in different time periods;onset time of drug;awakening time;Recovery time; | — |
Countries
China
Contacts
Public ContactJie Zhao
Hangzhou Red Cross Hospital
Outcome results
None listed