Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Healthy control group:NA
COPD acute exacerbation (moderate group):NA
COPD acute exacerbation (sever group) :NA
Sponsors
Jinhua Municipal Central Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: The patients who have moderate and severe COPD will be enrolled in our study. Their ages are between 40 and 75.
Exclusion criteria
Exclusion criteria: Patients with the following conditions will be excluded: ?Patients with pneumonia, active tuberculosis, pulmonary thromboembolism, interstitial lung disease, and lung cancer; ?Patients with autoimmune or immunodeficient disease. ?Patients treated with systemic glucocorticoids at a dose of = 20 mg/day; ? Patients with a history of other infectious diseases or who have used antibiotics within 2 weeks prior to the onset of the disease; ? Patients with psychiatric disorders, strokes, and those at greater risk of aspiration; ?Patients who do not wish to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T cell mitochondrial mass; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function;cytokine; | — |
Countries
China
Contacts
Public ContactDeng Yincan
Jinhua Municipal Central Hospital
Outcome results
None listed