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The basic and clinical research on endodontics and periapical diseases

The basic and clinical research on endodontics and periapical diseases

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074205
Enrollment
Unknown
Registered
2023-08-01
Start date
2019-07-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulpal and periapical disease

Interventions

Group 4 (In Vitro Experiment Part):Dynamic Navigation
Group 1 (Clinical Research Part):Freehand
Group 2 (Clinical Research Part):Dynamic Navigation
Group 3 (Clinical Research Part):Static Navigation
Group 5 (In Vitro Experiment Part):Static Navigation

Sponsors

Stomatological Hospital Affiliated to Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: (1) The tooth was failed to root canal therapy and diagnosed as refractory chronic periapical periodontitis, accompanied by serious destruction of periapical bone tissues and delayed healing of fistula, (2) The root canals were obviously overfilled and accompanied with obvious discomfort; (3) Root canal calcification with periapical shadow could not be cured by routine root canal therapy or failed to the treatment, (4) Root canal therapy complications such as lateral perforation and instrument separation could not be cured by routine root canal therapy; (5) CBCT should be performed preoperatively and postoperatively with a follow-up of at least 1 year.

Exclusion criteria

Exclusion criteria: (1)The affected teeth had severe periodontal disease or root fracture, (2) The affected teeth were residual roots with no value of retention, (3) The patients had systemic diseases such as diabetes mellitus that affected bone healing, (4)The patients were in the acute inflammatory stage, such as acute periapical periodontitis and acute osteomyelitis, (5) The patients with dentition defect on the same jaw as the affected teeth, (6) The patients who lost follow-up and incomplete case data were excluded.

Design outcomes

Secondary

MeasureTime frame
Global apex deviation;Apex horizontal deviation;Apex vertical deviation;

Primary

MeasureTime frame
Length deviation;Angle deviation;

Countries

China

Contacts

Public ContactYang Xuechao

Stomatological Hospital Affiliated to Guangzhou Medical University

xcyang@gzhmu.edu.cn+86 139 2879 4306

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026