Upper Respiratory Tract Infection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: -=18 years -Health care professionals and/or general population taking/not taking multivitamin tablets (Any Centrum multivitamin product) with at least 4 days per week and continuous supplementation for at least 3 months prior to the onset of infection. For example, to observe the endpoint of SARS-CoV-2 infection starts from early 15th December, 2022, participants should at least consecutively take multivitamin supplementation between early 13th September 2022 and 14thDecember 2022. -Able to understand the questionnaire and can provide clear start and end date of infection, duration and severity of symptoms, medications. Good compliance, able to cooperate with questionnaire survey and follow-up.
Exclusion criteria
Exclusion criteria: -Subjects with autoimmune disease and compromised immunity or on medication that can affect immune function -Pregnant or lactating women -Concurrently take other (multi)vitamins or minerals, protein powders or other nutritional supplements that can affect immunity -Participated in other drug clinical trials during investigation Mental impairment, unable to understand the nature, significance and expected consequences of the research, and/or with uncooperative attitude
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| COVID-19 infection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence rate and severity of Upper respiratory tract infection;Incidence rate of SARS CoV-2 infection; | — |
Countries
China
Contacts
Sun Yat-Sen Memorial Hospital Sun Yat-Sen University