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Establishment of immunity evaluation system on the sepsis and senile sepsis patients

Establishment of immunity evaluation system on the sepsis and senile sepsis patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074175
Enrollment
Unknown
Registered
2023-08-01
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: When patients meet all the following conditions, they can choose to enter the research: (1) Age 18 years or older; (2) Expected ICU hospitalization time longer than 48 hours; (3) Meets the diagnostic criteria of sepsis 3.0; (4) The patient or family member is able to understand the research protocol and is willing to participate in this study, providing written informed consent.

Exclusion criteria

Exclusion criteria: When a patient has any of the following conditions, they cannot be selected for clinical research: (1) Age<18 years old; (2) Pregnancy or lactation; (3) During chemotherapy, radiotherapy, and Targeted therapy for unhealed tumors, patients with immune diseases receiving immunosuppression or targeted drugs, and patients with granulocytopenia/lymphopenia due to blood system diseases or receiving immunosuppression treatment before the onset of sepsis; (4) An irrecoverable deathbed state; Abandoning treatment; (5) Other patients who do not meet the inclusion criteria.

Design outcomes

Primary

MeasureTime frame
28-day mortality;

Secondary

MeasureTime frame
Lymphocyte subtyping;mTOR;CTLA-4;

Countries

China

Contacts

Public ContactNa Cui

Peking Union Medical College Hospital

pumchcn@163.com+86 156 0121 2623

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 13, 2026