Prostatic hyperplasia, delirium, nausea and vomiting
Conditions
Interventions
Remazolam group (R group):Anesthesia induction and maintenance were performed with remimazolam as the leading agent
(P):Anesthesia induction and maintenance were performed with propofol as the leading agent
Sponsors
Deyang People's Hospital
Eligibility
Sex/Gender
Male
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1: age = 65 years old 2: American Society of Anesthesiologists Grade ?III 3: Patients undergoing elective transurethral resection of prostate
Exclusion criteria
Exclusion criteria: 1: patients with long-term benzodiazepine and opioid addiction 2: ASA> III, patients with poorly controlled severe cardiovascular and cerebrovascular disease (history of cerebrovascular accident, myocardial infarction, or unstable angina within 3 months, and preoperative blood pressure of 180/110 mmHg or above) 3: patients with drug allergy related to the study 4: patients with preoperative cognitive impairment and psycho-physical and psychiatric disorders 5: patients with preoperative cognitive impairment 6:Patient with severe liver and kidney dysfunction: BMI26.9 7: Patients with myasthenia gravis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to recovery from anesthesia or time to removal of laryngeal mask;Induction time of anesthesia;Heart rate, blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative VAS pain score;delirium;Resuscitation room stay time;Respiratory depression, nausea and vomiting;intraoperative awareness;Catheter-related bladder discomfort; | — |
Countries
China
Contacts
Public ContactChao Xiong
Deyang People's Hospital
Outcome results
None listed