Gastroesophageal reflux disease
Conditions
Interventions
experimental group:Take Jiangwei Anzhong Decoction
Control group:Take Rabeprazole
Sponsors
Fangshan Hospital of Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Western medical diagnosis is consistent with GERD; (2) Chinese medicine diagnosis of Stagnated Heat in Liver and Stomach; (3) Those who are between 18-75 years old; (4) Those who voluntarily participated and signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) Undiagnosed GERD, Chinese medicine identification is not Stagnated Heat in Liver and Stomach; endoscopic diagnosis of BE patients; (2) Recent history of taking medications that affect the gastrointestinal tract, such as glucocorticoids, aspirin, and calcium antagonists; (3) Combined organic upper gastrointestinal tract gastrointestinal disease (gastric ulcer, gastric cancer, etc.), primary esophageal dyskinesia; (4) Those with comorbid serious primary diseases of other systems; (5) Those with a history of surgery in the gastroesophageal area; (6) Pregnant and lactating women, and patients with disabilities (blindness, deafness, mute, intelligence, mental retardation, etc.) as defined by law; (7) Those with allergy, intolerance or contraindication to the drugs involved in this trial; (8) Patients who are also participating in clinical trials of other drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum 5-hydroxytryptamine(5-HT);serum VIP; | — |
Secondary
| Measure | Time frame |
|---|---|
| GerdQ Scale;Chinese Medicine Symptoms ClinRO Evaluation Scale;Self-Rating Anxiety Scale(SAS);Self-Rating Depression Scale(SDS); | — |
Countries
China
Contacts
Public ContactBoyi Jia
Fangshan Hospital of Beijing University of Chinese Medicine
Outcome results
None listed