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Research on Transcranial Direct Current Stimulation Intervention for Non-Suicidal Self-Injury Population

A Study on the Mechanism and Dynamic Changes of Pain Perception in People at Risk of Self Injury and Suicide

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074141
Enrollment
Unknown
Registered
2023-07-31
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-suicidal self-injury

Interventions

Real Group:1.5mA transcranial direct current stimulation over left dorsolateral prefrontal cortex (lDLPFC)
20 mins, single-session
Sham Group:Identical electrode montage, single-session sham transcranial direct current stimulation

Sponsors

Vanke School of Public Health, Tsinghua University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 29 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-29 years, right handed, regardless of gender; 2. At least 5 days of non-suicidal self-injury in the past year; 3. Normal or corrected-to-normal vision in both eyes; 4. Signed informed consent form.

Exclusion criteria

Exclusion criteria: 1. Allergic skin reactions or suffering from skin diseases; 2. History of seizure disorder or stroke; 3. Presence of tattoos or having had permanent makeup done in the last month; 4. No hair dyeing or perming in the past three months; 5. Presence of implanted medical devices or equipment (such as metal dentures, dental fillings with metal materials, dental braces, pacemakers, stents, cochlear implants, etc.); 6. Diagnosed with bipolar disorder, schizophrenia, or other psychotic disorders, obsessive-compulsive disorder, attention deficit hyperactivity disorder, autism, and other neurodevelopmental disorders, as well as borderline personality disorder; 7. Claustrophobia; 8. History of drug abuse or alcohol dependence; 9. Presence of congenital insensitivity to pain, peripheral nerve disorders, carpal tunnel syndrome, or Raynaud's disease; 10. Presence of chronic pain disorders, chronic inflammation, autoimmune, or other physical diseases; 11. History of head trauma or neurosurgical procedures; 12. Use of any psychotropic medication or participation in any psychological therapy in the past month or use of any analgesic medication (such as aspirin, ibuprofen, etc.) in the last 24 hours; 13. Previous experience with transcranial magnetic stimulation, transcranial electrical stimulation, or modified electroconvulsive therapy; 14. Participation in other electrical stimulation experiments within the last week or possibility of participating in other electrical stimulation experiments during the current study; 15. Currently at a serious risk of suicide; 16. Refusal to provide informed consent form.

Design outcomes

Primary

MeasureTime frame
Thermal stimulus-based fMRI neuroimaging data;Pain sensitivity;

Secondary

MeasureTime frame
Non-suicidal self-injury urge;Non-suicidal self-injury self efficacy;Non-suicidal self-injury resistance;Mood level;Mood level;

Countries

China

Contacts

Public ContactRunsen Chen

Vanke School of Public Health, Tsinghua University

runsenchen@tsinghua.edu.cn+86 188 0108 6627

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026