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Observation on the efficacy and safety of vitamin C + arginine + magnesium sulfate in patients with advanced lung cancer

Observation on the efficacy and safety of vitamin C + arginine + magnesium sulfate in patients with advanced lung cancer

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074134
Enrollment
Unknown
Registered
2023-07-31
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Single arm:Inject "vitamin C + arginine + magnesium sulfate" intravenously

Sponsors

Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Basic requirements for enrolled patients: 1. Lung cancer was diagnosed by pathology or cytology 2. According to the eighth edition of IASLC, the TNM staging of lung cancer is IV stage 3. Failure of multi-line therapy (third line or above) 4. The age is 18-80 years old, regardless of sex 5. The estimated survival time of the patients is no more than 3 months as assessed by 2 doctors with professional titles of deputy high school or above.

Exclusion criteria

Exclusion criteria: Exclusion criteria 1. Behavioral disorders with mental or cognitive impairment 2. Renal insufficiency or underlying kidney-related diseases 3. Liver insufficiency or underlying liver-related diseases 4. Allergic to vitamin C, arginine and magnesium sulfate 5. Complicated with the following diseases: hypermagnesemia, cysteinuria, gout, hyperoxaluria, uric acid nephrolithiasis, acidosis, diabetes, hemochromatosis, sideroblastic anemia, thalassemia, sickle cell anemia, myocardial damage, heart block, pulmonary edema, anuria 6. Pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
Treatment-related adverse events;;

Secondary

MeasureTime frame
Overall survival(OS);quality of life;

Countries

CHINA

Contacts

Public ContactWenhui Li

Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University)

2998384689@qq.com+86 138 8808 7323

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026