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A retrospective real-world study of prognostic factors associated with lung cancer with leptomeningeal metastases

A retrospective real-world study of prognostic factors associated with lung cancer with leptomeningeal metastases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074130
Enrollment
Unknown
Registered
2023-07-31
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Case series:None

Sponsors

The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patient =18 years old, male or female; 2) Lung cancer confirmed by histological or cytological pathology; 3) The researchers confirmed meningeal metastasis in the patients through comprehensive clinical evaluation, which included symptom evaluation, imaging evaluation or cerebrospinal fluid pathology evaluation; 4) have previously received anti-tumor therapy that meets the standard of clinical practice; 5) Prior treatment with radiation or surgery targeting the central nervous system is permitted; 6) Admission of patients without or with signs or symptoms of CNS;

Exclusion criteria

Exclusion criteria: 1) Currently combined with other tumors other than NSCLC; 2) Have other malignant tumors in the last 5 years or have a history of other malignant tumors, except skin basal cell carcinoma, cervical carcinoma in situ and breast ductal carcinoma in situ which have been effectively controlled

Design outcomes

Primary

MeasureTime frame
Treatment regimens and prognostic factors for lung cancer with meningeal metastasis;

Secondary

MeasureTime frame
Overall survival;Symptom improvement rate;

Countries

China

Contacts

Public ContactQiming Wang

The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital

qimingwang1006@126.com+86 187 0383 7615

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026