gingivitis
Conditions
Interventions
Probiotics intervention group:Probiotic toothpaste
Sponsors
Nanjing Stomatological Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 25-60 are in good health, free from systemic diseases and infectious diseases; (2) Meet the diagnostic criteria of periodontitis: PD > 4 mm, CAL > 3 mm, BOP positive; (3) There is no known food allergy or intolerance, and the physical examination is qualified; (4) Can accurately understand clinical trials and have good compliance.
Exclusion criteria
Exclusion criteria: (1) Smoking and volunteers in eat areca; (2) Have a history of periodontal treatment in the past six months; (3) receiving antibiotic treatment within one month or taking antibiotics during the study; Have participated in any clinical research in the past 30 days; (4) Used probiotic supplements or foods rich in probiotics, or antidiarrheal drugs within 30 days before or during the study; (5) Bad occlusal relationship and occlusal trauma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Saliva IgA content;Saliva microbial abundance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Saliva short-chain fatty acid content; | — |
Countries
China
Contacts
Public ContactXuna Tang
Nanjing Stomatological Hospital
Outcome results
None listed