renal failure
Conditions
Interventions
1:Using a region citrate anticoagulant infusion system to assist in anticoagulant infusion
2:Using the Fresenius Ci-Ca method to guide infusion pumps and injection pumps to assist anticoagulant infusion
Sponsors
shanghai ruijin hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) 18 years old = age = 80 years old, regardless of gender; (2) Diagnosed as acute or chronic renal failure, renal replacement therapy is required, and the researcher has determined that CRRT treatment is recommended; (3) Researchers determine that patients can establish stable vascular pathways; (4) The subjects and their guardians are able to understand the research purpose and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Drugs or preparations containing citric acid have been used within 72 hours, and blood transfusion treatment is expected to be required in clinical trials; (2) During the CRRT process, calcium supplementation therapy that is not required by the protocol is required; (3) Unable to establish a stable blood flow pathway for blood vessels (the pathway can provide a constant and effective blood flow greater than 200ml/min): (4) Previous allergies to extracorporeal circulation pipelines, blood purification equipment, blood exchange fluids, dialysate, citric acid, calcium containing solutions, etc; (5) Unable to tolerate CRRT treatment; (6) During the experiment, peritoneal dialysis needs to be used simultaneously; (7) Those with an ion calcium concentration in the body less than 0.95 or greater than 1.35 mmol/L; (8) Has participated or is currently participating in other clinical trials within 3 months from the date of signing the informed consent form; (9) Pregnant and lactating women; (10) Patients with active malignant tumors; (11) Expected survival time is less than 72 hours; (12) Other situations where the researcher determines that it is not suitable to participate in clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ionized calcium; | — |
Secondary
| Measure | Time frame |
|---|---|
| the accuracy of citrate pump ;the accuracy of calcium pump ; | — |
Countries
China
Contacts
Public ContactChen Xiaonong
shanghai ruijin hospital
Outcome results
None listed