Postoperative neurocognitive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age 60-80 years old; (2) Major non-cardiac surgery under general anesthesia, and the types of surgery are limited to radical gastrectomy, colon cancer, and rectal cancer;
Exclusion criteria
Exclusion criteria: (1) History of mental illness, such as anxiety, depression, schizophrenia; (2) traumatic brain injury, stroke, epilepsy, Parkinson's or Alzheimer's disease; (3) Other forms of cognitive decline (preoperative MMSE score <24); (4) chronic alcoholism; (5) There is obvious visual impairment; (6) Illiteracy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sleep-disorder;cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| delirium;Duration of surgery;tau/Aß42NFLHMGB-1IL-6TREM2; | — |
Countries
China
Contacts
Ningbo No.2 hospital