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To study the mechanism and influence of intestinal flora on early puberty in children under the condition of obesity

To study the mechanism and influence of intestinal flora on early puberty in children under the condition of obesity

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074047
Enrollment
Unknown
Registered
2023-07-28
Start date
2023-07-28
Completion date
Unknown
Last updated
2023-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity and early puberty

Interventions

Control group:No
CPP group:No
Obesity and CPP group:No

Sponsors

Chengdu Women and Children's Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 8.9 Years

Inclusion criteria

Inclusion criteria: 1) Children aged 7-8.9 years; 2) Meet the CPP diagnostic criteria according to the 2015 Chinese expert consensus on the diagnosis and treatment of central precocious puberty; 3) Children and adolescents aged 6 and above should be screened for overweight and obesity in School-age Children and adolescents by the People's Republic of China health industry standard "Overweight and Obesity Screening for School-age Children and Adolescents" released in 2018, and their BMI exceeds the 95th percentile of BMI of children of the same age and sex. They were admitted to the Department of Child Genetics, Endocrinology and Metabolism of Chengdu Women and Children's Central Hospital due to obesity or combined diseases. 4) The child and the guardian agree to participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) accompanied by other endocrine, digestive, nervous system and other diseases (such as severe obesity, diabetes, fatty liver, epilepsy, encephalitis, etc.) affecting weight or growth and development level, it may affect the formulation and implementation of intervention programs; 2) severe liver and kidney disease, tumors, recent infections, and any medical or mental illness that may affect study participation; 3) are participating in other studies, or have taken drugs that affect metabolism and have weight loss effects in the last 3 months; 4) The clinician has assessed that he is not eligible to participate in this study for other reasons. Will not be suitable to participate in this study. You will be examined by your study physician to confirm that you can participate in the study.

Design outcomes

Primary

MeasureTime frame
BMI;

Countries

China

Contacts

Public ContactChen Si

Chengdu Women's and Children's Central Hospital

liulansichen@163.com+86 188 1083 7466

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026