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Efficacy of surgical resection combined with intraperitoneal hyperthermic chemotherapy in the treatment of ruptured hepatocellular carcinoma:A retrospective study

Efficacy of surgical resection combined with intraperitoneal hyperthermic chemotherapy in the treatment of ruptured hepatocellular carcinoma:A retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074045
Enrollment
Unknown
Registered
2023-07-28
Start date
2023-07-30
Completion date
Unknown
Last updated
2023-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

Control Group (resection group):NA
Experimental Group (operation combined with intraperitoneal hyperthermic perfusion chemotherapy):NA

Sponsors

Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) according to the clinical diagnostic criteria of primary liver cancer (2022 edition) or confirmed by pathology/cytology, 2) preoperative diagnosis of rupture and hemorrhage of liver cancer was made by clinical manifestation, examination and imaging; 3) age 18-80 years old; 4) no surgery or systemic therapy (except interventional hemostasis) for the tumor before the initial operation; 5) Child-Pugh Class A or class B after liver protection and albumin correction, with no severe heart, lung or renal dysfunction and no absolute contraindication to surgery; 6) ECOG-PS score 0-1, with no other tumor disease; 7) no liver failure disease, 8) preoperative informed consent, 9) no postoperative major complications, such as massive hemorrhage, purulent infection, multiple organ failure, etc.

Exclusion criteria

Exclusion criteria: 1) having other active malignant tumor at the same time; 2) Child-pugh C grade with severe organic lesions of important organs and severe liver cirrhosis.

Design outcomes

Primary

MeasureTime frame
abdominal recurrence-free survival(RFS);

Secondary

MeasureTime frame
Over Survival;survival rate;

Countries

China

Contacts

Public ContactMingxin Pan

Zhujiang Hospital of Southern Medical University

pmxwxy@sohu.com+86 189 2891 8216

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026