sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Age 18 years; ? confirmed sepsis or septic shock and admitted in the ICU; ? met the definition and grading criteria of acute gastrointestinal injury (AGI); ? APACHE 2 score of 30 and treated stable; ? patient and family were informed and agreed to this study.
Exclusion criteria
Exclusion criteria: ? With severe acute central nervous system injury; ? severe thoracic and abdominal trauma; ? advanced malignancy, chronic disease; ? past history of severe gastrointestinal diseases, gastrointestinal surgery; ? intestinal obstruction, abdominal hypertension, acute gastrointestinal injury grade 4 or above; ? pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate of acute gastrointestinal injury;adverse event ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical ventilation time;ICU length of stay;APACHE? Score;SOFA Score;intra-abdominal pressure ;vital sign;Enteral nutrition tolerance; | — |
Countries
China
Contacts
Peking University Shenzhen Hospital