Diabetic nephropathy
Conditions
Interventions
Shenqi Dihuang decoction Group:SGLT-2 basic hypoglycemic treatment + Shenqi Dihuang Decoction, SGLT-2 once a day, one tablet each time, Shenqi Dihuang decoction twice in the morning and evening, 200ml
Control group:SGLT-2 basic hypoglycemic treatment
Sponsors
Kunshan Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Consistent with the diagnostic criteria for type 2 diabetes; (2) Consistent with the diagnosis of diabetic nephropathy; (3) Be between 18 and 75 years old; (4) Consistent with the diagnostic criteria of Qi-Yin injury; (5) The patient has informed consent and is willing to accept the corresponding treatment.
Exclusion criteria
Exclusion criteria: (1) Patients with acute diabetic complications such as diabetic ketoacidosis; (2) Patients with acute injury stress such as infection, shock, bleeding, severe dehydration, burn, etc. (3) Patients with malignant tumors and serious heart, liver, brain and kidney diseases; (4) Pregnant and lactating women; (5) People with primary kidney disease or secondary kidney disease for other reasons; (6) Patients with immune system diseases such as connective tissue diseases and rheumatic diseases; ? Allergic to or contraindicated with the drugs related to this study; (8) Use of GLP-1 Ra or DPP-4 inhibitors in the last three months; (9) Participants who are participating in or within 4 weeks of another clinical trial; (10) Cognitive impairment or poor compliance, inability to follow up, or mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary albumin creatinine ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ferritin;Free iron;Transferrin;Ceruloplasmin;Glutathione peroxidase GPX4;Malondialdehyde MDA;Acyl-coa synthetase Long Chain Family Member 4 (ACSL4); | — |
Countries
China
Contacts
Public ContactYuqiong Chen
Kunshan Hospital of Traditional Chinese Medicine
Outcome results
None listed