Obstructive sleep apnea
Conditions
Interventions
Adenotonsillectomy group:Adenotonsillectomy are performed by low-temperature plasma technique. Children are operated at department of Otolaryngology Head and Neck Surgery at BenQ Medical Center, Nanji
Watchful waiting group:Children randomized to watchful waiting will not receive any treatment for their OSA, surgical or medical, until the 6-month follow-up. They will be followed clinically and offe
Sponsors
Nanjing BenQ medical center
Eligibility
Sex/Gender
All
Age
10 Years to 12 Years
Inclusion criteria
Inclusion criteria: • =10 to <13 years of age • History or symptoms of OSA • Mild to moderate OSA, defined as an obstructive apnea-hypopnea index (OAHI) of =10 • Tonsil hypertrophy 1–4 according to Brodsky[10] • Parents understand the written information and answer the questionnaires
Exclusion criteria
Exclusion criteria: Recurrent tonsillitis • Obesity (BMI z-score = 3) • Neuromuscular disease • Chromosomal abnormality • Previous adeno-tonsillar surgery • Bleeding disorder • Cardiopulmonary disease • Conditions like hyperactivity disorder, etc., that may affect the results of polysomnography. • Previous upper airway surgery on the nose, pharynx or larynx, including tonsillectomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OAHI score change; | — |
Secondary
| Measure | Time frame |
|---|---|
| Other PSG parameters;OAHI subgroup analyses;OSA-18 questionnaire;Pediatric sleep questionnaire;Complications;Blood and tissue samples to be stored in a biobank for future research; | — |
Countries
China
Contacts
Public ContactZhenkun Yu
Department of Otolaryngology Head and Neck Surgery, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University
Outcome results
None listed