sarcoidosis
Conditions
Interventions
Gold Standard:Combining the pathological results of biopsy and the therapeutic effect after six months of treatment
Index test:pathological test from a specimen obtained by a 19G EBUS-TBNA needle
pathological test from a specimen obtained by a 22G EBUS-TBNA needle
Sponsors
Peking Union Medical Collage Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age at least 18 years 2. Clinical suspicion of sarcoidosis where EBUS-TBNA is being planned 3. Enlarged bilateral hilar and/or mediastinal lymph nodes >10 mm (any axis) on computed tomography of the chest 4. Ability to provide informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Asymmetric lymph nodes 2. Treatment with systemic glucocorticoids for >2 weeks in the preceding three months 3. Diagnosis of sarcoidosis possible with another minimally invasive technique such as skin biopsy or peripheral lymph node biopsy 4. Other test results verify the diagnosis of tuberculosis 5. Failure to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diagnostic yield of sarcoidosis with a new 19g TBNA needle; | — |
Secondary
| Measure | Time frame |
|---|---|
| diagnostic yield of sarcoidosis with a new 19g TBNA needle together with TBLB;diagnostic yield of sarcoidosis with a new 19g TBNA needle together with EBB; | — |
Countries
China
Contacts
Public ContactShao chi
Peking Union Medical Collage Hospital
Outcome results
None listed