The Natural Progression of Synovial FluidWhite Blood-Cell Counts, the Percentage of Polymorphonuclear Cells and Inflammatory Biomarkers After Primary Total Knee Arthroplast at early stage

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300073993

Enrollment

Unknown

Registered

2023-07-26

Start date

2023-04-01

Completion date

Unknown

Last updated

2023-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis

Interventions

Group of osteoarthritis:NA

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1)The investigator judged that the subjects met the surgical indications for primary total joint arthroplasty (hip/knee) surgery. (2)Subjects underwent unilateral primary total joint arthroplasty (hip/knee) at our center. (3)Age between 18 and 80 years old (inclusive).

Exclusion criteria

Exclusion criteria: (1) Patients complicated with malignant tumors, cardiovascular and cerebrovascular diseases and other serious diseases; (2) Abnormal coagulation function, thrombocytopenia and concurrent infection; (3) Patients who quit the experiment halfway.

Design outcomes

Primary

Measure	Time frame
synovial fluid white blood cell;Percentage of Polymorphonuclear Cells;alpha-defensin of synovial fluid;	—

Secondary

Measure	Time frame
CRP of synovial fluid;IL-6 of synovial fluid;calprotectin of synovial fluid;Leukocyte Esterase of synovial fluid;pH of synovial fluid;	—

Countries

China

Contacts

Public ContactCao Li

Medical Ethics Committee of the First Affiliated Hospital of Xinjiang Medical University

xjbone@sina.com+86 139 0991 0965

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026