Sedation of cardiac ultrasound in children
Conditions
Interventions
Dexmedetomidine combined with chloral hydrate group:Participants meeting inclusion criteria were sedated with dexmedetomidine combined with chloral hydrate
Dexmedetomidine combined with Midazolam group:Oral medication: (Midazolam oral solution 0.125ml. kg-1)+nasal medication: (dexmedetomidine 0.02ml. kg-1)
Sponsors
Children’s Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
0.6 Years to 4 Years
Inclusion criteria
Inclusion criteria: 1. Children who need sedation for cardiac ultrasonography; 2. Children aged 6 months to 4 years old who are unable to cooperate; 3. ASA I-III, non-cyanotic heart; 4. The guardian of the children will voluntarily participate and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Children known to be allergic to Midazolam, dexmedetomidine and chloral hydrate; 2. Children with intellectual or cognitive impairment who are unable to complete the corresponding assessment; (Brain injury, encephalomalacia, brain necrosis, intellectual disability, genetic diseases, various syndromes accompanied by developmental disorders); 3. Have used sedative and hypnotic drugs within the past 24 hours; 4. Excessive obesity refers to a body mass index (BMI) >= 23.9 kg/m^2; 5. Children who are unable to take medication orally due to their own illness; 6. Children who refuse to participate in the study; 7. Children with multiple history of sedation; 8. Excluding children who have slept within 2 hours; 9. Children with acute upper respiratory infections with symptoms of catarrh; 10. Children with sleep deprivation; 11. Drugs with synergistic effects; (see attachment) 12. Children with a Ramsay score greater than 3 during evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Children's acceptance;Onset time of the two groups;Ramsay sedation score every 5 minutes after medication;Recovery times; | — |
Countries
China
Contacts
Public ContactYing Xu
Children’s Hospital of Chongqing Medical University
Outcome results
None listed