Inflammatory pseudotumor following total hip arthroplasty of ceramic-on-ceramic friction interface
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: This study is a retrospective cohort study to review patients with inflammatory pseudotumor after total hip arthroplasty at the ceramic-ceramic friction interface in our hospital. Therefore, patients who had inflammatory pseudotumor after THA at the ceramic-ceramic friction interface and underwent total or partial hip revision in our hospital from February 2017 to February 2023 were included.
Exclusion criteria
Exclusion criteria: In this study, retrospective analysis was performed on patients with inflammatory pseudotumor after total hip arthroplasty at the ceramic-ceramic friction interface in our hospital. Therefore, patients with inflammatory pseudotumor after THA at the non-ceramic-ceramic friction interface who underwent total or partial hip revision in our hospital from February 2017 to February 2023 were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The wear measurement of ceramic implants;Elemental characterization of metal particles;Micrographs of metal particles;Pathological examination of inflammatory pseudotumor;Metal ion level in serum;Metal ion level in urine;Metal ion level in synovial fluid;Distribution of serum lymphocyte subsets;Serum cytokine measurement;Immune antibodies and complement measurement in serum;Immune antibodies and complement measurement in synovial fluid;Inflammatory pseudotumor histiocytic subpopulation;Maker;Inflammatory pseudotumor gene expression difference;Immune-related gene; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline detabese of patients;The type of inflammatory pseudotumor;Differential blood count;Inclination of acetabular cup;Anteversion of acetabular cup;C-reaction protein;Erythrocyte sedimentation rate;Total bilirubin;Direct bilirubin;Indirect bilirubin;Alanine aminotransferase;Aspartate aminotransferase;Urea;Creatinine;Estimated glomerular rate;Recurrence rate of inflammatory pseudotumor;Range of motion;Prosthetic survival rate; | — |
Countries
China
Contacts
West China Hospital, Sichuan University