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A study and analysis of inflammatory pseudotumor following total hip arthroplasty in patients with ceramic-ceramic friction interface

A study and analysis of inflammatory pseudotumor following total hip arthroplasty in patients with ceramic-ceramic friction interface

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073973
Enrollment
Unknown
Registered
2023-07-26
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory pseudotumor following total hip arthroplasty of ceramic-on-ceramic friction interface

Interventions

Inflammatory pseudomutor in ceramic-on-ceramic friction interface group:No

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: This study is a retrospective cohort study to review patients with inflammatory pseudotumor after total hip arthroplasty at the ceramic-ceramic friction interface in our hospital. Therefore, patients who had inflammatory pseudotumor after THA at the ceramic-ceramic friction interface and underwent total or partial hip revision in our hospital from February 2017 to February 2023 were included.

Exclusion criteria

Exclusion criteria: In this study, retrospective analysis was performed on patients with inflammatory pseudotumor after total hip arthroplasty at the ceramic-ceramic friction interface in our hospital. Therefore, patients with inflammatory pseudotumor after THA at the non-ceramic-ceramic friction interface who underwent total or partial hip revision in our hospital from February 2017 to February 2023 were excluded.

Design outcomes

Primary

MeasureTime frame
The wear measurement of ceramic implants;Elemental characterization of metal particles;Micrographs of metal particles;Pathological examination of inflammatory pseudotumor;Metal ion level in serum;Metal ion level in urine;Metal ion level in synovial fluid;Distribution of serum lymphocyte subsets;Serum cytokine measurement;Immune antibodies and complement measurement in serum;Immune antibodies and complement measurement in synovial fluid;Inflammatory pseudotumor histiocytic subpopulation;Maker;Inflammatory pseudotumor gene expression difference;Immune-related gene;

Secondary

MeasureTime frame
Baseline detabese of patients;The type of inflammatory pseudotumor;Differential blood count;Inclination of acetabular cup;Anteversion of acetabular cup;C-reaction protein;Erythrocyte sedimentation rate;Total bilirubin;Direct bilirubin;Indirect bilirubin;Alanine aminotransferase;Aspartate aminotransferase;Urea;Creatinine;Estimated glomerular rate;Recurrence rate of inflammatory pseudotumor;Range of motion;Prosthetic survival rate;

Countries

China

Contacts

Public ContactZeng Yi

West China Hospital, Sichuan University

zengyigd@126.com+86 189 8060 2289

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026