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Effect of trans-nasal humidified rapid insufflation ventilatory exchange on cerebral oxygen saturation in patients undergoing traumatic brain in jury emergency surgery during induction of general anesthesia

Application of transnasal humidified rapid-insufflation ventilatory exchange technology in patients undergoing surgery with different degrees of traumatic brain injury during the induction period of general anesthesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073951
Enrollment
Unknown
Registered
2023-07-26
Start date
2023-03-15
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatic brain injury

Interventions

Sponsors

Subei People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing general anesthesia surgery for acute TBI; (2) Age= 18 years old; (3) Eligible for HFNC oxygen therapy: normal spontaneous breathing, and airway patency; (4) Male or female

Exclusion criteria

Exclusion criteria: (1) ASA > IVE; (2) previous history of esophageal lesions and gastric surgery; (3) Have a history of nasal mucosal lesions, nasal surgery and trauma; (4) With the endotracheal tube into the operating room; (5) Poor postoperative outcome.

Design outcomes

Primary

MeasureTime frame
Regional Cerebral Oxygen Saturation;

Secondary

MeasureTime frame
The distal cross-sectional area;Optic nerve sheath diameter;For the first time to exhale during mechanical ventilation at the end of the co2 partial pressure;The incidence of hypoxemia during intubation;Residence time in the ICU;The hospitalization time;

Countries

China

Contacts

Public ContactGao Ju

Subei People's Hospital

gaoju_300@qq.com+86 180 5106 3988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026