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Correlations between postoperative delayed neurocognitive recovery and the plasma levels of a-synuclein and NFL in elderly patients undergoing gastrointestinal tumor surgery

Correlations between postoperative delayed neurocognitive recovery and the plasma levels of a-synuclein and NFL in elderly patients undergoing gastrointestinal tumor surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073947
Enrollment
Unknown
Registered
2023-07-25
Start date
2023-07-31
Completion date
Unknown
Last updated
2023-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive dysfunction

Interventions

Group P:no Intervention
Group N:no Intervention

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1: Patients undergoing laparoscopic surgery for gastrointestinal tumors 2: Age= 65 years 3: American Society of Anesthesiologists (ASA) grade II~III 4: MMSE= 24 points 5: Patients and their families voluntarily participate and sign informed consent forms

Exclusion criteria

Exclusion criteria: A history of neurological disorders, family history of psychiatric disorders, and language and cognitive dysfunction cannot be used to complete cognitive tests

Design outcomes

Primary

MeasureTime frame
cognitive function;neurofilament light chain protein;a-synuclein;S100ß;—

Countries

China

Contacts

Public ContactLei enjun

The First Affiliated Hospital of Nanchang University, Donghu District, Nanchang City, Jiangxi Provin

leienjun@126.com+86 139 7001 9906

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026