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Clinical evaluation of safety and effectiveness of femtosecond LASer-assisted flap manufacturing LASIK combined with accelerated crosslinking in correction of high myopia

Clinical evaluation of safety and efficacy of FS-LASIK combined with accelerated crosslinking in correction of high myopia - Clinical evaluation of safety and efficacy of FS-LASIK combined with accelerated crosslinking in correction of high myopia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073933
Enrollment
Unknown
Registered
2023-07-25
Start date
2019-05-10
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ametropia

Interventions

FS-LASIK Xtra group:Corneal accelerated cross-linking
Conventional LASIK group:no intervention

Sponsors

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age = 18 years old; surgery simple myopia or refractory myopia with astigmatism, best corrected visual acuity = 0.8; preoperative diopter: spherical mirror -1.00 ~ -11.00 D, cylindrical degree = - 5. 00 D, the refractive power is stable for more than 2 years; the central corneal thickness is greater than 460um, the postoperative corneal stroma thickness is greater than 280um; the patient should stop wearing at least 2 weeks of soft contact lens, stop wearing hard contact lens for 8 weeks or stop wearing 3~6 Months Orthokeratology.

Exclusion criteria

Exclusion criteria: Exclusion criteria: patients with eye diseases or eye surgery history; Patients with subclinical keratoconus; Scar constitution, immune disease or connective tissue disease; Have mental symptoms such as depression.

Design outcomes

Primary

MeasureTime frame
uncorrected visual acuity(UCVA);dioptric;Corneal biomechanical index;corneal curvature;Corneal endothelium count;Best correctionn visual acuity;

Secondary

MeasureTime frame
corneal epithelial thickness;cornea densito;

Countries

China

Contacts

Public ContactJi Peng

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine

ji6605@126.com+86 135 7375 3812

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026