postoperative sleep quality
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Thoracoscopy radical resection of lung cancer under general anesthesia,surgical time = 2 hours; 2.Age:30~80years old; 3.BMI:18-30kg/?; 4.ASA:?~?; 5.Primary tumor,without undergoing radiotherapy or chemotherapy before surgery; 6.Normal cognitive function.
Exclusion criteria
Exclusion criteria: 1.Refusal to participate in this study; 2.Communication disorder, inability to cooperate with researchers, such as language comprehension disorder, mental illness, epilepsy, Parkinson's disease history or Myasthenia gravis; 3.Identified/suspected of having a history of alcohol, analgesics or other drug abuse and addiction; 4.Contraindications for transcutaneous electrical stimulation, including local skin damage, infection or implantation of electrophysiological devices in the body; 5.Have received similar acupuncture or TEAS treatment before; 6.Preoperative visit for patients with blood pressure = 180/110 mm Hg (WHO-ISH guideline for grade 3 hypertension); 7.Individuals who experience unstable angina or myocardial infarction within 3 months; Heart function NYHA grading =?; 8.Patients with severe liver and kidney dysfunction (severe liver dysfunction: ALT, conjugated bilirubin, AST, ALP, total bilirubin, one of which>2 times the upper limit of normal value; severe renal dysfunction: Cr clearance rate177umol/L); 9.Complications of diabetes with Complications of diabetes (Great vessels disease, diabetes nephropathy, retinopathy, diabetes cardiomyopathy, diabetes neuropathy, Diabetic foot, etc.); 10.COPD GOLD:III~IV, pulmonary fibrosis, uncontrolled asthma; 11.History of lung surgery and patients transitioning to open chest surgery; 12.Patients with poor postoperative pain relief; 13.Patients with Sleep disorder such as obstructive apnea and restless legs syndrome; 14.Participated in other clinical trials within 3 months prior to enrollment in the study; 15.The supervising doctor or researcher believes that there are other situations that are not suitable for participating in this study (reasons need to be recorded: such as interference from family environment).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep duration ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality;mRNA and protein levels of TIM in PBMCs and EVs during operation;Postoperative hospitalization time;NRS pain grade; | — |
Countries
China
Contacts
Tangdu Hospital, Air Force Military Medical University