Parkinson
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for PD; 2. The Hoehn-Yahr grading of Parkinson's disease was 1-3 grade; 3. Age 40-85 years; 4. At least one limb scored at least 2 or higher on the tremor, stiffness, postural stability, or bradykinesia component of the MDS-UPDRS III motor component of the Sinicization Unified Parkinson's Disease Rating Scale; 5. Stable PD drug use; 6. The ability to stand independently and walk with or without an aid; 7. Not exercising regularly for the last three months (at least three times a week for at least 20 minutes at a time) ; 8. No contraindications to magnetic resonance imaging; 9. Subjects gave informed consent, volunteered, and were willing to be assigned to any intervention group.
Exclusion criteria
Exclusion criteria: 1. There was some degree of cognitive impairment (the mini-mental state scale score was less than 24) . 2. History of mental illness, severe aphasia, visual and hearing impairment, or severe organ failure, musculoskeletal system disease, coronary heart disease, myocardial infarction, and other contraindications to exercise therapy. 3. Is participating in other clinical trials that may affect the outcome of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gait analysis (the angles of the joints of the lower limbs at different time phases in the sagittal plane);Dynamic balance (Lyapunov index and center of gravity position);Coordination Analysis (movement coordination of two or more adjacent joints);Observation of brain morphology;Observation of brain function activity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall PD function level (MDS-UPDRS evaluation);Balance function (Berg balance scale);Coordination Function (integrated coordination scale); | — |
Countries
China
Contacts
Fujian University of Traditional Chinese Medicine