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The multicenter accurate diagnosis study for emphysema based on lung random parition in CT quantification algorithm

The multicenter accurate diagnosis study for emphysema based on lung random parition in CT quantification algorithm

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073917
Enrollment
Unknown
Registered
2023-07-25
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Interventions

Gold Standard:Fleischner Society visual system
Index test:accurate diagnosis study for emphysema based on lung random parition in CT quantification algorithm

Sponsors

shengjing hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Inclusion criteria: a. The patient is older than 18 years; b. HRCT images of the lungs. C. HRCT shows emphysema: ? Lobular central type: small hole shaped and small round low-density areas are scattered in the lung, with a diameter of 2 mm to 4 mm. They are located in the center of the pulmonary lobule. The pulmonary vessels are normal, and the lesions are mostly distributed in the pulmonary lobule area; ? Total lobular type: the low-density area distributed diffusely in both lungs is not closed, with irregular size and shape. Most of the lower lobes are dominated, and the pulmonary vascular texture in the diseased area becomes thinner and smaller; ? Parainterlobular septal emphysema: involving the end of the lobule, most of them are subpleural, umbilical vein, esophageal recess, left ventricle and near the anterior commissure line, showing subpleural pulmonary bullae, and most of the lung shows localized air sacs in the lung, losing the structure of pulmonary parenchyma, with regular walls, and no pulmonary vessels can be seen inside.

Exclusion criteria

Exclusion criteria: (2) Exclusion criteria: a. HRCT images show imaging changes that interfere with the evaluation and calculation of emphysema, such as lung cancer, interstitial lung disease, bronchiectasis, pleural effusion, pneumothorax, hydropneumothorax, mediastinal emphysema, pulmonary infection, etc; b. Unable to export the original HRCT data from the Display imaging system;

Design outcomes

Primary

MeasureTime frame
The proportion of low-density attenuation areas with CT values below -950HU to bilateral lung volume;;Accuracy;Sensitivity ;Specificity ;Positive predicative value;Negative predictive value;

Countries

China

Contacts

Public ContactZHAO LI

shengjing hospital of China Medical University

lzhaoli@163.com+86 189 4025 1639

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026