Perioperative neurocognitive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients ranged in age from 60 to 85 years old. Complete clinical data; The ASA grade was ?~?, and the surgical site was lung. Preoperative MMSE score was > 26 points.
Exclusion criteria
Exclusion criteria: Patients with uncontrolled diseases such as severe cardiac, liver and renal dysfunction or malignant tumor before operation; Patients with neurological or psychiatric history; Patients who take hypnotics, narcotic analgesics, antidepressants and anti-anxiety drugs for a long time; Patients with coagulation dysfunction; Poor compliance or other reasons unable to cooperate with researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum adiponectin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum cAMP;Serum PKA;Serum AQP4;Serum BDNF; | — |
Countries
China
Contacts
The Tenth Affiliated Hospital of Southern Medical University (Dongguan People's Hospita