A clinical study of the safety and efficacy of polymyxin B in critically ill elderly patients

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300073896

Enrollment

Unknown

Registered

2023-07-25

Start date

2021-12-01

Completion date

Unknown

Last updated

2023-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe infection

Interventions

Old group:No

Young and middle-aged group:No

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ?Critically ill patients with multidrug-resistant Gram-negative bacteria infection; ? Prescribed with polymyxin B=72h; ?Age=18 years

Exclusion criteria

Exclusion criteria: ?Anuria or requiring renal replacement therapy; ?Pregnant women

Design outcomes

Primary

Measure	Time frame
AUCss, 24h;Css, avg;	—

Secondary

Measure	Time frame
clinical responese;28d mortality;Microbiological eradication;occurrence of acute kidney injury during polymyxin B treatment;length of ICU stay;	—

Countries

China

Contacts

Public ContactJiang Jinjiao

Shandong Provincial Hospital Affiliated to Shandong First Medical University

jjjsch@163.com+86 186 7887 7551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026