sarcopenia
Conditions
Interventions
Control group:none
sarcopenia group:Daily Intake of Probiotics (Probio-M8)
Sponsors
Hainan General Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: ?The subject's grip strength meets the following criteria: males = 12 s. ?Age >= 60 years, both sexes ?Signed informed consent
Exclusion criteria
Exclusion criteria: ?various acute and chronic infections and other immune diseases, such as end-stage renal disease, liver failure, heart failure, respiratory failure; or with malignancy. ?endocrine diseases such as abnormal thyroid function, Cushing's syndrome, abnormal pituitary function. ?history of antibiotics, probiotic preparations or diarrhea and gastroenteritis within two weeks prior to the experiment within one month.. ?The requirement to take anti-osteoporosis drugs, glucocorticoids, thyroid hormones, sex hormones, acid production, etc., during the trial. ?history of long-term alcohol consumption, i.e., drinking for more than five years, or ethanol amount > 140 g/week in men and > 70 g/week in women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| grip;appendi-cular skeletal muscle mass;5-time chair stand test;triglyceride;cholesterol;high density lipoprotein cholesterol;low density lipoprotein cholesterin;globulin;albumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal flora;Fecal metabolome;Serum metabolome; | — |
Countries
China
Contacts
Public ContactYangli He/ Jiachao Zhang
School of Food Science and Engineering, Hainan University, Haikou, Hainan, China
Outcome results
None listed