Topics initiated by our researchers
Conditions
Interventions
Tocilizumab + standard treatment group:NA
baricitinib + standard treatment group:NA
Sponsors
Shenzhen Second Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: ( 1 ) Age > 18 years ; ( 2 ) PCR-positive COVID-19 infection confirmed by any specimen ( e.g., respiratory tract, blood, urine, feces, other body fluids ) ; ( 3 ) Confirmed as pneumonia by CT scan or chest X-ray ;
Exclusion criteria
Exclusion criteria: ( 1 ) Death within 24 hours of admission ( 2 ) Patients requiring mechanical ventilation within 24 hours of admission ( 3 ) Active tuberculosis infection, suspected active bacterial, fungal, viral or other infection ( except for COVID-19 )
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative proportion of all-cause deaths or patients requiring mechanical ventilation as of day 28; | — |
Secondary
| Measure | Time frame |
|---|---|
| On the 28 th day, the median time of discharge or ' preparation for discharge ' or the median time of clinical status improvement; | — |
Countries
China
Contacts
Public ContactWang Meiying
Shenzhen Second Hospital
Outcome results
None listed