Xerostomia Edentulism
Conditions
Interventions
Lingual nerve stimulation treatment group:Electrical stimulation + mechanical stimulation
Placebo group:Mechanical stimulation
Sponsors
School of Stomatology, The Fourth Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1)Age 18 or above; 2) The unstimulated salivary flow rate was no more than 0.15mL/min, but the stimulated salivary flow rate was at least 2 times that of unstimulated salivary flow rate(If unstimulated saliva flow rate is 0, stimulated saliva more than 0 can be included); 3) The Kapur index of complete denture is less than 6; 4) Patients who have undergone complete denture restoration for more than 1 month; 5) Complete dentures are well made and fit with mucous membrane; 6)Patients who wear the complete denture have no pain, cheek biting, tongue biting, nausea and other discomfort symptoms; 7) Normal intelligence and mental condition, able to answer correctly, able to cooperate with the test; 8) Patients have been informed and has voluntarily signed written informed consent.
Exclusion criteria
Exclusion criteria: 1)HIV or active HBV or HCV infection; 2)Serious cardiopulmonary, liver, kidney, blood and other systemic diseases; 3)Patients receiving chemoradiotherapy for head and neck tumors with a history of transplantation; 4)Participants using anticoagulants; 5)Allergic to lingual nerve stimulation devices; 6)Having an intellectual or psychological disorder; 7)Wear a pacemaker, a defibrillator, a hearing aid; 8)Epilepsy and involuntary muscle movement disorders (such as Parkinson's or Hoddington's disease); 9)Pregnancy 10)Patients with chronic or recurrent erosive or ulcerative or precancerous or malignant oral lesions;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of retaining force of complete denture;Improvement of retaining force of complete denture; | — |
Secondary
| Measure | Time frame |
|---|---|
| Unstimulated and stimulated salivary flow;Distribution and change of bite force;Changes in the severity of dry mouth;Improvements in quality of life;Patients' satisfaction with the complete denture after treatment; | — |
Countries
China
Contacts
Public ContactLina Niu
School of Stomatology, The Fourth Military Medical University
Outcome results
None listed