Helicobacter pylori infection
Conditions
Interventions
Experimental group:Vonoprazan + Amoxicillin + Clarithromycin + bismuth pectin
control group:Rabeprazole + Amoxicillin + Clarithromycin + bismuth pectin
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age 18-70 years old; 2) Positive results from any test such as C14 breath test, C13 breath test, and gastroscopy pathology; 3) Comply with the recommended indications for eradicating HP in the sixth national consensus report on HP infection management in China [15]; 4) Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) those who do not cooperate with the treatment; 2) those who have mental illness, heart, liver, kidney and other vital organ insufficiency before admission; 3) women who are planning to be pregnant, pregnant and breastfeeding; 4) those who are allergic to the drugs used in this study; 5) those who have used bismuth and antimicrobial drugs in the 4 weeks prior to the treatment, and those who have used PPIs and H2-receptor antagonists in the 2 weeks prior to the treatment; 6) those who have history of surgery for upper GI disorders; and 7) those who are addicted to alcohol or any other any condition that increases the risk of adverse reactions to treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rate after treatment;Adverse reactions; | — |
Countries
China
Contacts
Public ContactQiao Wang
The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed